The LIFECODES Family of Products
LIFECODES KIR Typing
The KIR SSO typing kit utilizes the Luminex xMAP technology and an SSO methodology for identifying the various KIR loci present in a sample. The KIR loci identified with this product
are:
Killer cell immunoglobulin-like receptors (KIR) play a role in regulating the functional activity of Natural Killer (NK) cells. Expressed on the surface of NK cells and some T cells, they recognize HLA Class I molecules found on the surface of target cells. These receptors can be either inhibitory or activating in nature.
In haploidentical hematopoietic stem cell transplantation, there is evidence that when the recipient lacks the inhibitory HLA ligand for the donor’s NK cells, there can be an NK-cell alloreaction. This reaction can be in the GVL direction and can also help prevent GVHD.
- Premade master mix includes primers, dNTPs and PCR buffer eliminating extra steps and consumables
- Homogeneous assay eliminates the need for centrifugation and wash steps saving time and reducing the chances of pipeting errors
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Catalog Number
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Description
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545110
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LIFECODES KIR SSO Typing Kit
(20 tests/kit) For Research Use Only
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